Interleukin 27 (IL-27) is an immune-regulatory protein that is produced by tumor cells and many immune cells; however, its diverse effects are not well understood. Therefore, Dr. Anthony Phan is examining it to determine whether it’s responsible for pro-tumor or anti-tumor effects. Determining how IL-27 impacts T cell function within the tumor will be essential to understanding the complex tumor environment, and the insights produced from Dr. Phan's studies should provide important information that can aid the development of novel strategies that enable immunotherapy to further improve patient outcomes.
University of Pennsylvania | All Cancers | 2017 | Christopher A. Hunter, Ph.D.
*Immunotherapy results may vary from patient to patient.
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New research, new treatments, and how we’re working toward a future immune to cervical cancer
Ugur Sahin and Ozlem Tureci, two of this year’s CRI Coley Award recipients, are pioneers of the mRNA vaccines helping us confront COVID-19 and cancer.