Cancer and the Immune System:
The Vital Connection

We recognize that patients and caregivers looking into cancer immunotherapy
as a potential treatment option often face an uphill battle in understanding
the technical language of immunology. To help explain the science behind immunotherapy, we have prepared this free, downloadable guide:
Cancer and the Immune System: The Vital Connection (12MB PDF).

Cancer and the Immune System: The Vital Connection - Cover

This ebook will equip you with a basic understanding of cancer biology, how our immune system works, and the range of rapidly developing treatments that fall into the category of immunotherapies as well as definitions for the terminology of immuno-oncology.

Download the EBook

Table of contents

Introduction: Revisiting the “C” word

Part 1: What is cancer?

  • 1.1 Cell Division, Mutations, and Cancer
  • 1.2 How Cancer Develops
  • 1.3 Cancer Incidence and Mortality in the U.S.
  • 1.4 Cancer and the Immune System

Part 2: The human immune system

  • 2.1 Innate Immunity: Our First Line of Defense
  • 2.2 Adaptive Immunity: Learning the Enemy’s Tricks
  • 2.3 Inflammation: Linking Innate and Adaptive Immunity
  • 2.4 The Humoral Immune Response: Making Antibodies
  • 2.5 The Cellular Immune Response: Making “Killer” T Cells
  • 2.6 Tolerance and the Problem of Autoimmunity

Part 3: Cancer immunotherapy

  • 3.1 Historical Origins
  • 3.2 Non-Specific Immune Stimulants
  • 3.3 Antibody Immunotherapies
  • 3.4 Cancer Vaccines
  • 3.5 Checkpoint Blockade
  • 3.6 Adoptive Cell Therapy
  • 3.7 Combinations: The Future of Cancer Immunotherapy


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