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A History of Making History

CRI stands at the center of the immunotherapy revolution. The legacy of our founders is tumor immunology, which has significantly improved outcomes for millions of cancer patients around the world, and promises to help millions more. 

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Pioneering progress

The number of people dying from cancer in the U.S. has declined by more than 30 percent over the past three decades. Immunotherapy is one of the key factors contributing to this remarkable statistic. As the founders of tumor immunology, CRI continues as the frontrunner in the field. We invite you to learn about the institutional milestones, scientific discoveries, and people involved in making CRI the primary authority in cancer immunotherapy. 

Transforming Cancer Treatment

We are the leaders of a revolution that has transformed the landscape of cancer treatment. As we celebrate over 70 years of relentless pursuit and innovation, CRI’s journey is a testament to the power of immunotherapy. 

James Allison

“Virtually no one thought immunotherapy would work… until it finally did.”

James Allison, PHD

The University of Texas MD Anderson Cancer Center 
2018 Nobel Laureate 
Director, CRI Scientific Advisory Council

The Path Forward

Backed by CRI funding, scientists at nearly every major research institution are pushing the boundaries of immunotherapy—bringing bold ideas and fresh talent into the fight against cancer. Clinical trials are where this progress becomes real, connecting patients to tomorrow’s treatments today and driving breakthroughs that save lives. Whether you’re a patient, researcher, or supporter, clinical trials are where you can make a real impact.

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The Journey Continues as Vigorously as Ever.

CRI will continue to be a pioneer and leader in bringing immunotherapies to more cancer patients by: 

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Seeking innovative partnerships with biotech and pharmaceutical companies that are developing promising immunotherapies in their drug pipelines.


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Collaborating with disease-specific cancer charities seeking to extend their research portfolio into clinical immunology.


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Funding basic science and training future generations of scientists.


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Educating patients and caregivers about their immunotherapy treatment options and encouraging them to advance research through participation in clinical trials.