An Interactive Table of Cancer Immunotherapy Options

This table lists immunotherapies that have been approved by the U.S. Food and Drug Administration (FDA) to treat different types of cancer. Some treatments are only used for specific groups of patients based on factors such as cancer type, stage, or biomarkers or genetic testing. The color dots in the table indicate the type of immunotherapy for each treatment.

Key: Immune Checkpoint Inhibitor (ICI) Non-ICI Immunomodulator Cell and Gene Therapy Bispecific Antibody Cancer Vaccine Oncolytic Virus Therapy
Immunotherapy
Cancers Treated
Immunotherapy
Cancers Treated

Afamitresgene autoleucel (Tecelra®)

A modified T cell that targets MAGE-A4 on tumor cells

Sarcoma

Lisocabtagene maraleucel (Breyanzi®)

A CD19-targeting CAR T-cell immunotherapy

Follicular Lymphoma, Large B-Cell Lymphoma, Mantle Cell Lymphoma, Marginal Zone Lymphoma

Aldesleukin (Proleukin®)

A cytokine that targets the IL-2/IL-2R pathway

Melanoma, Renal Cell Carcinoma (a type of kidney cancer)

Mogamulizumab (Poteligeo®)

A monoclonal antibody that targets the CCR4 pathway

Cutaneous T-Cell Lymphoma

Atezolizumab (Tecentriq®)

A checkpoint inhibitor that targets the PD-1/PD-L1 pathway

Alveolar Soft Part Sarcoma, Hepatocellular Carcinoma (a type of liver cancer), Melanoma, Non-Small Cell Lung Cancer, Small Cell Lung Cancer

Mosunetuzumab (Lunsumio®)

A bispecific antibody that targets CD20 on lymphoma cells and CD3 on T cells

Follicular Lymphoma

Avelumab (Bavencio®)

A checkpoint inhibitor that targets the PD-1/PD-L1 pathway

Bladder Cancer, Merkel Cell Carcinoma (a type of skin cancer), Renal Cell Carcinoma (a type of kidney cancer)

Nadofaragene firadenovec (Adstiladrin®)

An adenoviral vector-based gene therapy

Bladder Cancer

Axicabtagene ciloleucel (Yescarta®)

A CD19-targeting CAR T-cell immunotherapy

Follicular Lymphoma, Large B-Cell Lymphoma

Nivolumab (Opdivo®)

a checkpoint inhibitor that targets the PD-1/PD-L1 pathway*

Bladder Cancer, Colorectal Cancer, Esophageal Cancer, Gastric (Stomach) Cancer, Head and Neck Cancer, Hepatocellular Carcinoma (a type of liver cancer), Hodgkin Lymphoma, Melanoma, Mesothelioma, Non-Small Cell Lung Cancer, Renal Cell Carcinoma (a type of kidney cancer)

Bacillus Calmette-Guérin (BCG) vaccine

Uses weakened bacteria to stimulate the immune system

Bladder Cancer

Nogapendekin alfa inbakicept (Anktiva®)

A cytokine that targets the IL-15 pathway

Bladder Cancer

Blinatumomab (Blincyto®)

A bispecific antibody that targets CD19 on tumor cells and CD3 on T cells

Acute Lymphoblastic Leukemia

Obecabtagene autoleucel (Aucatzyl®)

A CD19-targeting CAR T-cell immunotherapy

Acute Lymphoblastic Leukemia

Brexucabtagene autoleucel (Tecartus®)

A CD19-targeting CAR T-cell immunotherapy

Acute Lymphoblastic Leukemia, Mantle Cell Lymphoma

Peginterferon alfa-2b (Sylatron™)

A cytokine that targets the interferon pathway

Melanoma

Cemiplimab (Libtayo®)

A checkpoint inhibitor that targets the PD-1/PD-L1 pathway

Basal Cell Carcinoma (a type of skin cancer), Cutaneous Squamous Cell Carcinoma (a type of skin cancer), Non-Small Cell Lung Cancer

Pembrolizumab (Keytruda®)

A checkpoint inhibitor that targets the PD-1/PD-L1 pathway

Biliary Tract Cancer, Bladder Cancer, Breast Cancer, Cervical Cancer, Colorectal Cancer, Cutaneous Squamous Cell Carcinoma (a type of skin cancer), Endometrial Cancer, Esophageal Cancer, Gastric (Stomach) Cancer, Hepatocellular Carcinoma (a type of liver cancer), Head and Neck Cancer, Hodgkin Lymphoma, Melanoma, Mesothelioma, Merkel Cell Carcinoma (a type of skin cancer), Non-Small Cell Lung Cancer, Primary Mediastinal Large B-Cell Lymphoma, Renal Cell Carcinoma (a type of kidney cancer), MSI-H or dMMR Cancers, TMB-High Cancers

Ciltacabtagene autoleucel (Carvykti®)

A BCMA-targeting CAR T-cell immunotherapy

Multiple Myeloma

Penpulimab (Anniko®)

A checkpoint inhibitor that targets the PD-1/PD-L1 pathway

Nasopharyngeal Carcinoma (a type of head and neck cancer)

Cosibelimab (Unloxcyt™)

A checkpoint inhibitor that targets the PD-1/PD-L1 pathway

Cutaneous Squamous Cell Carcinoma (a type of skin cancer)

Retifanlimab (Zynyz®)

A checkpoint inhibitor that targets the PD-1/PD-L1 pathway

Anal Cancer, Merkel Cell Carcinoma (a type of skin cancer)

Dostarlimab (Jemperli®)

A checkpoint inhibitor that targets the PD-1/PD-L1 pathway

Endometrial Cancer, MSI-H or dMMR Cancers

Sipuleucel-T (Provenge®)

A vaccine composed of patient-stimulated dendritic cells

Prostate Cancer

Durvalumab (Imfinzi®)

A checkpoint inhibitor that targets the PD-1/PD-L1 pathway

Biliary Tract Cancer, Bladder Cancer, Endometrial Cancer, Gastric (Stomach) Cancer, Non-Small Cell Lung Cancer, Small Cell Lung Cancer

Talimogene laherparepvec (T-VEC) (Imlygic®)

A modified herpes simplex virus (HSV) that infects tumor cells and promotes their destruction

Melanoma

Elranatamab (Elrexfio®)

A bispecific BCMA-directed CD3 T-cell engager

Multiple Myeloma

Talquetamab (Talvey®)

A bispecific antibody that targets GPRC5D on tumor cells and CD3 on T cells

Multiple Myeloma

Epcoritamab (Epkinly®)

A bispecific antibody that targets CD20 on tumor cells and CD3 on T cells

Diffuse Large B-Cell Lymphoma, Follicular Lymphoma

Tarlatamab (Imdelltra®)

A bispecific antibody that targets DLL3 on cancer cells and CD3 on T cells

Small Cell Lung Cancer

Glofitamab (Columvi®)

A bispecific antibody that targets CD20 on tumor cells and CD3 on T cells

Diffuse Large B-Cell Lymphoma

Tebentafusp (Kimmtrak®)

A bispecific T-cell engager that targets a gp100 peptide on cells and CD3 on T cells

Uveal Melanoma

Idecabtagene vicleucel (Abecma®)

A BCMA-targeting CAR T-cell immunotherapy

Multiple Myeloma

Teclistamab (Tecvayli®)

A bispecific antibody that targets BCMA on tumor cells and CD3 on T cells

Multiple Myeloma

Imiquimod (Aldara®)

An immune adjuvant targeting the TLR7 pathway

Basal Cell Carcinoma (a type of skin cancer)

Tisagenlecleucel (Kymriah®)

A CD19-targeting CAR T-cell immunotherapy

Acute Lymphoblastic Leukemia, Follicular Lymphoma, Large B-Cell Lymphoma

Ipilimumab (Yervoy®)

A checkpoint inhibitor that targets the CTLA-4 pathway#

Melanoma

Tislelizumab (Tevimbra®)

A checkpoint inhibitor that targets the PD-1/PD-L1 pathway

Esophageal Cancer, Gastric (Stomach) Cancer

Lifileucel (Amtagvi®)

A tumor-derived T-cell immunotherapy

Melanoma

Toripalimab (Loqtorzi™)

A checkpoint inhibitor that targets the PD-1/PD-L1 pathway

Nasopharyngeal Carcinoma (a type of head and neck cancer)

Linvoseltamab (Lynozyfic™)

A bispecific BCMA-directed CD3 T-cell engager

Multiple Myeloma

Tremelimumab (Imjudo®)

A checkpoint inhibitor that targets the CTLA-4 pathway

Hepatocellular Carcinoma (a type of liver cancer), Non-Small Cell Lung Cancer

* Nivolumab + #ipilimumab can be used to treat patients with colorectal cancer and hepatocellular carcinoma (a type of liver cancer).
* Nivolumab + relatlimab (Opdualag®) can be used to treat patients with melanoma.