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IN THE NEWS
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Scientists use salmonella bug to kill cancer cells
Reuters – 8/11/10 – Treating tumors with salmonella bacteria can induce an immune response that kills cancer cells.

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Publication Alert: Caltech biologists discover microRNAs that control function of blood stem cells
ScienceBlog – 8/4/10 – CRI Postdoctoral Fellow Ryan O’Connell is first author on a paper describing a novel role for microRNA-125b in controlling blood stem cell fate.

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FDA Grants Orphan Drug Status for Personalized Cancer Vaccine, BiovaxID®, Targeting Mantle Cell Lymphoma
MarketWatch – 7/26/10 – The U.S. Food and Drug Administration granted orphan drug status for Biovest’s cancer vaccine, BiovaxID®, for mantle cell lymphoma.

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BMS Files Ipilimumab With FDA And EMA, Positioning It for Launch Next Year
The Pink Sheet Daily – 7/22/10 – Bristol-Myers Squibb submitted regulatory filings for the melanoma immunotherapy ipilimumab with the U.S. FDA and European Medicines Agency at the end of June.

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Publication Alert: CRI Investigator Adolfo Ferrando, M.D., Ph.D., in Nature Immunology
Nature Immunology – 7/11/10 – Depletion of the RNA-binding proteins ZFP36L1 and ZFP36L2 leads to perturbed thymic development and T lymphoblastic leukemia.

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CRI Investigator Named to Top Position at U.K. Immunology Research Group
Cancer Research Institute – 7/21/10 – Cancer Research Institute clinical investigator Vincenzo Cerundolo, a professor of immunology at the Weatherall Institute of Molecular Medicine at the University of Oxford, U.K., has been named director of the Medical Research Council (MRC) Human Immunology Unit.

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Cervical cancer vaccine 'may prevent more cases than initially thought'
Cancer Research UK – 7/14/10 – A study by scientists at the Health Protection Agency, the University of Manchester, and the Manchester Royal Infirmary suggests that the cervical cancer vaccine could prevent even more cases of the disease than previously thought.  (Click here for more information on the cervical cancer vaccine and CRI’s role in it.)

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IMPORTANT DATES
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Aug. 19 - Fashion Fights Cancer

Sep. 13 - 16th Annual Golf Challenge

Oct. 1 - Fellowship Award Application Deadline

Oct. 6-8 - 18th CRI Symposium

Oct. 8-11 - Conquer the Canyon

CANCER SURVIVAL STORY

Sharon Belvin and baby Lilian

Sharon Belvin's "untreatable" late-stage malignant melanoma went into complete remission after she received an investigational immune-based therapy called anti-CTLA-4 monoclonal antibody developed and administered by Cancer Research Institute scientists. 

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