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The Cancer Research Institute is proud to announce its Technology Impact Award, a new program designed to challenge the world's leading scientists and out-of-the box thinkers to create a research plan and assemble a research team that will develop a new technology platform with the potential to transform the field of cancer immunotherapy.

The grant aims to support the development of highly innovative technologies that can ultimately be adopted by the research community at large and that will enable researchers to develop the next generation cancer immunotherapies that can be effective and personalized for each patient. Technologies may facilitate our understanding of the antigenic profile, cellular interplay, and mechanistic pathways within the tumor microenvironment that are essential for an effective anti-tumor response.

Award Focus

The most competitive applicants will address focus areas where disruptive technological innovation stands to benefit the field and cancer patients most, including but not limited to:

  • New bioinformatics methods or technologies that speed collection and analysis of large sets of patient-derived biological data
  • Artificial platforms such as computer simulations for modeling biological systems and responses to immunotherapy
  • Tools and methods that improve profiling of tumors to inform therapeutic strategies
  • Real-time visualizations of molecular and cellular activity to improve tracking of responses to immunotherapy

Applicant Eligibility and Selection Criteria

  • The grant will be awarded to a scientist leading a cross-functional team who describes an extraordinarily novel, yet practical research plan that is creative and technically sophisticated.
  • Applicants must hold a faculty appointment as a tenure-track assistant professor (or higher rank) at the time of award activation.
  • The winning project must result in new tools and/or methodologies that improve cancer immunotherapy research worldwide.

Structure and Financial Information

  • The grant will be awarded to a single investigator
  • One grant of up to $1,000,000 is available, payable over a maximum of three years
  • Deductions for administrative overhead or indirect costs of any kind are not permitted. Payments are made quarterly in U.S. currency to the host institution

Application Deadlines

The deadline for the receipt of the Letter of Intent is November 15. Candidates will be notified by January 16 whether or not they have been invited to submit a full grant proposal. The full application is due March 15.

Instructions for Letters of Intent Submission

Letters of intent must be submitted electronically. Once you access the application, you will be asked to create a user account unique to you, which will catalogue all applications you submit to CRI. If you have submitted a grant application to CRI in the past, please login with your existing user account.

After you have filled out all required fields on the online form, you will be asked on the final page of the application to upload, in this order, the following supporting documentation in one PDF document:

  • Abstract of research in nontechnical English explaining the significance of the new technology platform and its impact on the field of cancer immunotherapy. Not to exceed 250 words.
  • An initial research concept (succinct description of the proposed research plan with specific aims and timelines, description of the how the proposed technology platform has the potential to transform the field of cancer immunotherapy), not to exceed 3 pages.
  • Brief description of your current research.
  • Curriculum vitae and bibliography (limit bibliography to past 5 years or publications relevant to proposed research).
  • If applicable, curriculum vitae for all group members, as well as a description of each member's research focus.

Only PDF documents will be accepted. All files must be combined into one document and named according to the following formula: if your name is John Brown, your file should be called Brown John.pdf. Do not submit multiple attachments.

When you have finished uploading the attachments, click "Submit." You will receive a notice confirming that you have successfully submitted your Application Form. Immediately after, an automated notification from CRI will be sent to your email address, also confirming submission.

If you encounter problems uploading your attachment, email it to Be sure to note the application number, which will be assigned to you at the time of submission.

Online applications will be accepted until 5 p.m. Eastern Time on the deadline date. If the deadline falls on the weekend, applications will be accepted until the close of business that following Monday. We strongly suggest submitting your applications as early as possible to provide ample time in case your application is incomplete. Incomplete applications will not be considered.

Formatting Guidelines

Any documents you attach to your online application form must be typed single-space using a 12 pt. or larger font size.

*Immunotherapy results may vary from patient to patient.