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Glucose is an important energy source for our cancer-killing T cells. In kidney tumors, however, poor nutrient conditions often disrupt T cell metabolism and inhibit their anti-cancer activity. Dr. Beckermann is characterizing how exactly the tumor environment perturbs T cell metabolism. Then, using patients’ cells and mouse models, she’s developing approaches to support T cells and restore their normal metabolism. The insights she uncovers might then suggest ways to target and improve the effectiveness of these anti-cancer T cells in immunotherapies for patients.
Vanderbilt University | Breast Cancer, Kidney Cancer, Lung Cancer, Melanoma | 2016 | Jeffrey Rathmell, Ph.D.
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Dr. Ansuman Satpathy is building a single-cell atlas to help us better understand why immunotherapy succeeds or fails in certain patients.
While many are adjusting to virtual fundraisers at the moment, the Epic Film Guys now have plenty of experience, running their fourth fundraiser May 27-31, 2020.