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Congratulations to the 2018 Nobel Prize in Physiology or Medicine Winners Read More

University of Pennsylvania School of Medicine
Philadelphia, PA

Dr. E. John Wherry is the director of the Institute for Immunology and a professor in the Department of Microbiology at the University of Pennsylvania School of Medicine. Dr. Wherry’s expertise lies mainly in T cell exhaustion, which can hamper anti-tumor immune responses. He’s helped advance our understanding of how gene expression changes affect this exhaustion, which has led to strategies to improve the effectiveness of T cell-targeting immunotherapies. In recognition of his achievements, Dr. Wherry received the 2016 Frederick W. Alt Award for New Discoveries in Immunology, and is also member of CRI’s Clinical Leadership Committee.

[Our major goal] is to understand the mechanisms of T cell exhaustion during chronic infections and cancer.
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