{"id":33530,"date":"2025-01-17T15:35:22","date_gmt":"2025-01-17T20:35:22","guid":{"rendered":"https:\/\/www.cancerresearch.org\/?post_type=cri_scientists&#038;p=33530"},"modified":"2025-02-11T12:10:53","modified_gmt":"2025-02-11T17:10:53","slug":"anca-apavaloaei-phd","status":"publish","type":"cri_scientists","link":"https:\/\/www.cancerresearch.org\/es\/cri-funded-scientists\/anca-apavaloaei-phd","title":{"rendered":"Anca Apavaloaei, PhD"},"content":{"rendered":"\n<p>Anca Apavaloaei, PhD is a postdoctoral researcher at Weill Cornell Medicine, where she\u2019s pioneering the development of off-the-shelf anti-cancer vaccines targeting LINE-1-derived antigens. LINE-1, a retrotransposon that remains active in cancer cells, could provide a novel source of tumor antigens for immune-targeting therapies. Her research aims to identify these antigens and test if vaccines targeting them could enhance immune responses in a broad range of cancers, from gastroesophageal to melanoma and lung cancer.&nbsp;<\/p>\n\n\n\n<p>With a strong foundation in immunology and data science, Dr. Aprovaloaei\u2019s journey began in 2013, where her work on MHC class I peptide selection led to important insights into immune recognition of disease. During her PhD at the University of Montreal, she furthered her expertise by applying computational techniques to uncover new tumor antigen targets for vaccine development, culminating in a Best Thesis Award.&nbsp;<\/p>\n\n\n\n<p>\u201cBy targeting the unique molecular programs that drive cancer, we can harness the immune system to fight tumors in a more precise and effective way,\u201d says Dr. Aprovaloaei. Her ongoing work at Weill Cornell, alongside Dr. Taha Merghoub and Dr. Benjamin Greenbaum, is a promising step toward novel cancer immunotherapies.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Projects and Grants<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Identification of LINE-1 Derived Antigens for Development of Off-the-Shelf Anti-Cancer Vaccines\u00a0<\/h3>\n\n\n\n<p>Weill Cornell Medicine | All Cancers | 2025 | Taha Merghoub, PhD, and Benjamin Greenbaum, PhD<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Anca Apavaloaei, PhD is a postdoctoral researcher at Weill Cornell Medicine, where she\u2019s pioneering the development of off-the-shelf anti-cancer vaccines targeting LINE-1-derived antigens. LINE-1, a retrotransposon that remains active in cancer cells, [&hellip;]<\/p>\n","protected":false},"featured_media":33536,"template":"","tax_cancer_type":[455],"tax_grant_type":[486],"tax_award_year":[742],"tax_institutions":[538],"tax_location_states":[494],"class_list":["post-33530","cri_scientists","type-cri_scientists","status-publish","has-post-thumbnail","hentry"],"acf":{"scientist_subhead":"CRI Carson Family Charitable Trust Foundation Immuno-Informatics Fellow","quote":"","scientist_last_name":"Apavaloaei","show_on_landing":true,"scientist_publish_until":"20271231"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Anca Apavaloaei, PhD - Cancer Research Institute<\/title>\n<meta name=\"description\" content=\"CRI Immuno-Informatics Postdoctoral Fellow Anca Apavaloaei, PhD, is researching LINE-1-derived antigens to develop cancer vaccines.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.cancerresearch.org\/cri-funded-scientists\/anca-apavaloaei-phd\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Anca Apavaloaei, PhD - Cancer Research Institute\" \/>\n<meta property=\"og:description\" content=\"CRI Immuno-Informatics Postdoctoral Fellow Anca Apavaloaei, PhD, is researching LINE-1-derived antigens to develop cancer vaccines.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.cancerresearch.org\/cri-funded-scientists\/anca-apavaloaei-phd\" \/>\n<meta property=\"og:site_name\" content=\"Cancer Research Institute\" \/>\n<meta property=\"article:modified_time\" content=\"2025-02-11T17:10:53+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.cancerresearch.org\/wp-content\/uploads\/2025\/01\/Photo_ApavaloaeiAnca.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"800\" \/>\n\t<meta property=\"og:image:height\" content=\"533\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Tiempo de lectura\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutos\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.cancerresearch.org\/cri-funded-scientists\/anca-apavaloaei-phd\",\"url\":\"https:\/\/www.cancerresearch.org\/cri-funded-scientists\/anca-apavaloaei-phd\",\"name\":\"Anca Apavaloaei, PhD - Cancer Research Institute\",\"isPartOf\":{\"@id\":\"https:\/\/www.cancerresearch.org\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.cancerresearch.org\/cri-funded-scientists\/anca-apavaloaei-phd#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.cancerresearch.org\/cri-funded-scientists\/anca-apavaloaei-phd#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.cancerresearch.org\/wp-content\/uploads\/2025\/01\/Photo_ApavaloaeiAnca.jpg\",\"datePublished\":\"2025-01-17T20:35:22+00:00\",\"dateModified\":\"2025-02-11T17:10:53+00:00\",\"description\":\"CRI Immuno-Informatics Postdoctoral Fellow Anca Apavaloaei, PhD, is researching LINE-1-derived antigens to develop cancer vaccines.\",\"breadcrumb\":{\"@id\":\"https:\/\/www.cancerresearch.org\/cri-funded-scientists\/anca-apavaloaei-phd#breadcrumb\"},\"inLanguage\":\"es\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.cancerresearch.org\/cri-funded-scientists\/anca-apavaloaei-phd\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"es\",\"@id\":\"https:\/\/www.cancerresearch.org\/cri-funded-scientists\/anca-apavaloaei-phd#primaryimage\",\"url\":\"https:\/\/www.cancerresearch.org\/wp-content\/uploads\/2025\/01\/Photo_ApavaloaeiAnca.jpg\",\"contentUrl\":\"https:\/\/www.cancerresearch.org\/wp-content\/uploads\/2025\/01\/Photo_ApavaloaeiAnca.jpg\",\"width\":800,\"height\":533},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.cancerresearch.org\/cri-funded-scientists\/anca-apavaloaei-phd#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.cancerresearch.org\/es\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Anca Apavaloaei, PhD\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.cancerresearch.org\/#website\",\"url\":\"https:\/\/www.cancerresearch.org\/\",\"name\":\"Cancer Research Institute\",\"description\":\"For a World Immune to Cancer\",\"publisher\":{\"@id\":\"https:\/\/www.cancerresearch.org\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.cancerresearch.org\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"es\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.cancerresearch.org\/#organization\",\"name\":\"Cancer Research Institute\",\"url\":\"https:\/\/www.cancerresearch.org\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"es\",\"@id\":\"https:\/\/www.cancerresearch.org\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.cancerresearch.org\/wp-content\/uploads\/2025\/05\/logo-gradient.svg\",\"contentUrl\":\"https:\/\/www.cancerresearch.org\/wp-content\/uploads\/2025\/05\/logo-gradient.svg\",\"width\":156,\"height\":53,\"caption\":\"Cancer Research Institute\"},\"image\":{\"@id\":\"https:\/\/www.cancerresearch.org\/#\/schema\/logo\/image\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Anca Apavaloaei, PhD - Cancer Research Institute","description":"CRI Immuno-Informatics Postdoctoral Fellow Anca Apavaloaei, PhD, is researching LINE-1-derived antigens to develop cancer vaccines.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.cancerresearch.org\/cri-funded-scientists\/anca-apavaloaei-phd","og_locale":"es_ES","og_type":"article","og_title":"Anca Apavaloaei, PhD - Cancer Research Institute","og_description":"CRI Immuno-Informatics Postdoctoral Fellow Anca Apavaloaei, PhD, is researching LINE-1-derived antigens to develop cancer vaccines.","og_url":"https:\/\/www.cancerresearch.org\/cri-funded-scientists\/anca-apavaloaei-phd","og_site_name":"Cancer Research Institute","article_modified_time":"2025-02-11T17:10:53+00:00","og_image":[{"width":800,"height":533,"url":"https:\/\/www.cancerresearch.org\/wp-content\/uploads\/2025\/01\/Photo_ApavaloaeiAnca.jpg","type":"image\/jpeg"}],"twitter_card":"summary_large_image","twitter_misc":{"Tiempo de lectura":"2 minutos"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.cancerresearch.org\/cri-funded-scientists\/anca-apavaloaei-phd","url":"https:\/\/www.cancerresearch.org\/cri-funded-scientists\/anca-apavaloaei-phd","name":"Anca Apavaloaei, PhD - Cancer Research Institute","isPartOf":{"@id":"https:\/\/www.cancerresearch.org\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.cancerresearch.org\/cri-funded-scientists\/anca-apavaloaei-phd#primaryimage"},"image":{"@id":"https:\/\/www.cancerresearch.org\/cri-funded-scientists\/anca-apavaloaei-phd#primaryimage"},"thumbnailUrl":"https:\/\/www.cancerresearch.org\/wp-content\/uploads\/2025\/01\/Photo_ApavaloaeiAnca.jpg","datePublished":"2025-01-17T20:35:22+00:00","dateModified":"2025-02-11T17:10:53+00:00","description":"CRI Immuno-Informatics Postdoctoral Fellow Anca Apavaloaei, PhD, is researching LINE-1-derived antigens to develop cancer vaccines.","breadcrumb":{"@id":"https:\/\/www.cancerresearch.org\/cri-funded-scientists\/anca-apavaloaei-phd#breadcrumb"},"inLanguage":"es","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.cancerresearch.org\/cri-funded-scientists\/anca-apavaloaei-phd"]}]},{"@type":"ImageObject","inLanguage":"es","@id":"https:\/\/www.cancerresearch.org\/cri-funded-scientists\/anca-apavaloaei-phd#primaryimage","url":"https:\/\/www.cancerresearch.org\/wp-content\/uploads\/2025\/01\/Photo_ApavaloaeiAnca.jpg","contentUrl":"https:\/\/www.cancerresearch.org\/wp-content\/uploads\/2025\/01\/Photo_ApavaloaeiAnca.jpg","width":800,"height":533},{"@type":"BreadcrumbList","@id":"https:\/\/www.cancerresearch.org\/cri-funded-scientists\/anca-apavaloaei-phd#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.cancerresearch.org\/es"},{"@type":"ListItem","position":2,"name":"Anca Apavaloaei, PhD"}]},{"@type":"WebSite","@id":"https:\/\/www.cancerresearch.org\/#website","url":"https:\/\/www.cancerresearch.org\/","name":"Cancer Research Institute","description":"For a World Immune to Cancer","publisher":{"@id":"https:\/\/www.cancerresearch.org\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.cancerresearch.org\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"es"},{"@type":"Organization","@id":"https:\/\/www.cancerresearch.org\/#organization","name":"Cancer Research Institute","url":"https:\/\/www.cancerresearch.org\/","logo":{"@type":"ImageObject","inLanguage":"es","@id":"https:\/\/www.cancerresearch.org\/#\/schema\/logo\/image\/","url":"https:\/\/www.cancerresearch.org\/wp-content\/uploads\/2025\/05\/logo-gradient.svg","contentUrl":"https:\/\/www.cancerresearch.org\/wp-content\/uploads\/2025\/05\/logo-gradient.svg","width":156,"height":53,"caption":"Cancer Research Institute"},"image":{"@id":"https:\/\/www.cancerresearch.org\/#\/schema\/logo\/image\/"}}]}},"fimg_url":"https:\/\/www.cancerresearch.org\/wp-content\/uploads\/2025\/01\/Photo_ApavaloaeiAnca.jpg","_links":{"self":[{"href":"https:\/\/www.cancerresearch.org\/es\/wp-json\/wp\/v2\/cri_scientists\/33530","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.cancerresearch.org\/es\/wp-json\/wp\/v2\/cri_scientists"}],"about":[{"href":"https:\/\/www.cancerresearch.org\/es\/wp-json\/wp\/v2\/types\/cri_scientists"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.cancerresearch.org\/es\/wp-json\/wp\/v2\/media\/33536"}],"wp:attachment":[{"href":"https:\/\/www.cancerresearch.org\/es\/wp-json\/wp\/v2\/media?parent=33530"}],"wp:term":[{"taxonomy":"tax_cancer_type","embeddable":true,"href":"https:\/\/www.cancerresearch.org\/es\/wp-json\/wp\/v2\/tax_cancer_type?post=33530"},{"taxonomy":"tax_grant_type","embeddable":true,"href":"https:\/\/www.cancerresearch.org\/es\/wp-json\/wp\/v2\/tax_grant_type?post=33530"},{"taxonomy":"tax_award_year","embeddable":true,"href":"https:\/\/www.cancerresearch.org\/es\/wp-json\/wp\/v2\/tax_award_year?post=33530"},{"taxonomy":"tax_institutions","embeddable":true,"href":"https:\/\/www.cancerresearch.org\/es\/wp-json\/wp\/v2\/tax_institutions?post=33530"},{"taxonomy":"tax_location_states","embeddable":true,"href":"https:\/\/www.cancerresearch.org\/es\/wp-json\/wp\/v2\/tax_location_states?post=33530"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}