{"id":11199,"date":"2016-12-06T00:00:00","date_gmt":"2016-12-06T00:00:00","guid":{"rendered":"https:\/\/www.cancerresearch.org\/media-room\/cancer-research-institute-and-fibrolamellar-cancer-foundation-announce-partnership-to-fund-cancer-immunotherapy-research-in-ultra-rare-liver-cancer\/"},"modified":"2022-07-13T04:21:24","modified_gmt":"2022-07-13T04:21:24","slug":"cri-and-fibrolamellar-cancer-foundation-partner-up","status":"publish","type":"cri_news","link":"https:\/\/www.cancerresearch.org\/es\/media-room\/cri-and-fibrolamellar-cancer-foundation-partner-up","title":{"rendered":"Cancer Research Institute and Fibrolamellar Cancer Foundation Announce Partnership to Fund Cancer Immunotherapy Research in Ultra-Rare Liver Cancer"},"content":{"rendered":"\n<p>The Cancer Research Institute (CRI), a nonprofit organization dedicated to funding cancer immunotherapy research for all types of cancer, and the <a href=\"https:\/\/fibrofoundation.org\/\" target=\"_blank\" rel=\"noopener\">Fibrolamellar Cancer Foundation<\/a> (FCF), a nonprofit organization devoted to funding research in a rare but deadly form of liver cancer called fibrolamellar hepatocellular carcinoma (FHC), today announced that they have partnered to provide $641,500 to four outstanding scientists whose research is focused on developing immunotherapies for patients with FHC.<\/p>\n\n\n\n<p>FHC is considered an \u201cultra-rare\u201d disease, affecting approximately 200-300 people per year worldwide, mostly teens and young adults. Additionally, there is a high unmet need in both ongoing research efforts and the development of effective treatments. To date, no formal studies of the effectiveness of immunotherapy in the treatment of FHC have been undertaken.<\/p>\n\n\n\n<p>The Cancer Research Institute\/Fibrolamellar Cancer Foundation Fellowships and Grants are the first research awards designated to help understand the potential role for immunotherapy in treating patients with this type of liver cancer.<\/p>\n\n\n\n<p>\u201cAs the largest funder of fibrolamellar research, we are committed to exploring all appropriate research approaches to find a cure\u2013sooner than later,\u201d said John Hopper, executive director of the Fibrolamellar Cancer Foundation. \u201cLeveraging CRI&#8217;s tremendous depth of experience in immunotherapy fills a need to explore this therapy approach for our patient community,\u201d Hopper added.<\/p>\n\n\n\n<p>Cancer immunotherapy is a new approach to treating cancer that has been proven to benefit patients with a variety of cancer types, including melanoma, non-small cell lung cancer, kidney cancer, head and neck cancer, and others. This treatment approach harnesses the immune system\u2019s natural ability to protect the body against cancer.<\/p>\n\n\n\n<p>\u201cThrough this funding, we seek to stimulate interest in this rare type of cancer and spur discoveries that may ultimately lead to lifesaving new immunotherapies for FHC patients,\u201d said<\/p>\n\n\n\n<p>Jill O\u2019Donnell-Tormey, PhD, CEO and director of scientific affairs at the Cancer Research Institute. \u201cThe Cancer Research Institute\u2019s partnership with the Fibrolamellar Cancer Foundation reinforces our commitment to leveraging our expertise in immunotherapy to benefit efforts in treating all types of cancer, particularly those that are rare and under-researched,\u201d O\u2019Donnell-Tormey added.<\/p>\n\n\n\n<p>In July 2016, the Cancer Research Institute issued an open call for applications to fellowship candidates seeking to explore the potential role for immunotherapies in the treatment of FHC. Applications were reviewed by CRI\u2019s Postdoctoral Fellowship Review Committee, which twice annually vets highly competitive applications from young scientists working in top immunology and tumor immunology laboratories around the world.<\/p>\n\n\n\n<p>The three recipients of the Cancer Research Institute\/Fibrolamellar Cancer Foundation Fellowship are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Kevin C. Barry, PhD, University of California, San Francisco, San Francisco, CA<\/li><li>Sofia L. Novais De Oliveira, PhD, University of Wisconsin-Madison, Madison, WI<\/li><li>Kevin Michael Sullivan, MD, University of Washington School of Medicine, Seattle, WA<\/li><\/ul>\n\n\n\n<p>Additionally, a Cancer Research Institute\/Fibrolamellar Cancer Foundation Grant has been awarded to:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Amy K. Kim, MD, Johns Hopkins University, Baltimore, MD<\/li><\/ul>\n\n\n\n<p>\u201cWe now have the tools to rapidly determine the immune context of rarer types of cancer for which, like fibrolamellar hepatocellular carcinoma, there is a dearth of treatment options and that have gone understudied with respect to immunotherapy,\u201d said Ellen Pur\u00e9, PhD, professor and chair, Department of Biomedical Sciences, University of Pennsylvania School of Veterinary Medicine and chair, CRI Postdoctoral Fellowship Review Committee.<\/p>\n\n\n\n<p>\u201cThis new initiative will fund four studies that, by being conducted in parallel, will in a cost and time effective manner provide insights into the immune context of FHC, determine whether FHC is a good candidate for immune-based therapies, and pave the way for translation of immune-based therapies for FHC to the clinic.\u201d<\/p>\n\n\n\n\n\n<p><strong>About Fibrolamellar Hepatocelluar Carcinoma<\/strong><br>Fibrolamellar hepatocellular carcinoma (FHC) is a rare liver cancer that usually occurs in teens and young adults who have no history of liver disease. FHC occurs in only 1 in 5,000,000 people and is considered an ultra-rare cancer. Typical symptoms include abdominal, shoulder or back pain, loss of appetite, weight loss, jaundice, and occasionally a palpable mass, and are usually associated with advanced disease. The typical treatment is surgical removal of the tumor, which can be curative if done before the tumor has spread, or metastasized. When the tumor cannot be removed surgically or when there is distant spread, other therapies may be used to slow down the spread of the disease. There is no standard regimen so non-surgical therapy varies from patient to patient. These therapies are not typically curative but may shrink tumors for a period of time. New treatments that offer curative potential in patients with advanced disease are urgently needed.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The two nonprofits partnered to support four scientists whose research is focused on developing immunotherapies for patients with &nbsp;fibrolamellar hepatocellular carcinoma.<\/p>\n","protected":false},"featured_media":2650,"template":"","tags":[99],"resource_cancer_types":[],"resource_patient_age":[],"resource_cancer_stage":[],"resource_treatment_type":[],"resource_treatment_status":[],"class_list":["post-11199","cri_news","type-cri_news","status-publish","has-post-thumbnail","hentry","tag-partnerships"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Cancer Research Institute and Fibrolamellar Cancer Foundation Announce Partnership to Fund Cancer Immunotherapy Research in Ultra-Rare Liver Cancer - Cancer Research Institute<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.cancerresearch.org\/media-room\/cri-and-fibrolamellar-cancer-foundation-partner-up\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Cancer Research Institute and Fibrolamellar Cancer Foundation Announce Partnership to Fund Cancer Immunotherapy Research in Ultra-Rare Liver Cancer - 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