Specific bacterial species can stimulate immune cells known as antigen-presenting cells (APCs), which in turn contribute to diverse T cell responses (including those against tumors) but the identities of the specific APC subsets involved remain unclear. Therefore, Dr. Ranit Kedmi is using molecular and genetic approaches to probe these relationships. Ultimately, she aims to uncover insights that will lay the foundation for the future development of bacteria-based and dendritic cell-based cancer immunotherapies that can overcome pro-tumor immunosuppression and instead promote anti-tumor T cell responses.
New York University Medical Center | All Cancers | 2017 | Dan R. Littman, M.D., Ph.D.
*Immunotherapy results may vary from patient to patient.
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