MicroRNAs (miRNAs) are a type of RNA that control protein production and cell behavior by regulating other RNAs. miRNA-155 in particular influences immune cell activity and has been implicated in several cancers. By creating a database that compares the genetic activity of immune cells with and without miRNA-155, Dr. Hsin is working to uncover which RNAs are targeted by miRNA-155, and under what conditions. Moving forward, those insights may help broaden our overall understanding of miRNA-mediated gene regulation and aid in the development of approaches to address abnormal miRNA activity.
Memorial Sloan Kettering Cancer Center | Breast Cancer, Lung Cancer, Lymphoma | 2014 | Alexander Y. Rudensky, Ph.D.
*Immunotherapy results may vary from patient to patient.
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Dr. E. John Wherry dicusses cell therapies and the cancer ecosystem during Day 3 of the 2022 CRI-ENCI-AACR International Cancer Immunotherapy Conference (CICON22).
Drs. Stefani Spranger and Elsa Anagnostou recap highlights relating to myeloid cells, tumor heterogeneity, and preclinical models from Day 2 of of the 2022 CRI-ENCI-AACR International Cancer Immunotherapy Conference (CICON22).