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MicroRNAs (miRNAs) are a type of RNA that control protein production and cell behavior by regulating other RNAs. miRNA-155 in particular influences immune cell activity and has been implicated in several cancers. By creating a database that compares the genetic activity of immune cells with and without miRNA-155, Dr. Hsin is working to uncover which RNAs are targeted by miRNA-155, and under what conditions. Moving forward, those insights may help broaden our overall understanding of miRNA-mediated gene regulation and aid in the development of approaches to address abnormal miRNA activity.
Memorial Sloan Kettering Cancer Center | Breast Cancer, Lung Cancer, Lymphoma | 2014 | Alexander Y. Rudensky, Ph.D.
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New research, new treatments, and how we’re working toward a future immune to cervical cancer
Ugur Sahin and Ozlem Tureci, two of this year’s CRI Coley Award recipients, are pioneers of the mRNA vaccines helping us confront COVID-19 and cancer.