While the immune system can eliminate cancer, it can also contribute to cancer growth under certain conditions. HMGB1 is an important immune molecule that plays a role in this process and may have immense value in the clinic. Dr. Bassi wants to understand more about its activity, so he’s analyzing tumor-immune interactions in a mouse cancer model and determining how differential HMGB1 activity influences breast cancer progression as well as responses to immunotherapy and chemotherapy. In this way, he hopes to reveal insights about new targets that guide new approaches to improve patient outcomes.
University Health Network (Canada) | Breast Cancer | 2016 | Tak W. Mak, Ph.D.
*Immunotherapy results may vary from patient to patient.
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This September for Childhood Cancer Awareness Month, we look at new research, new treatments, and how we are working toward a future immune to childhood cancer.
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