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Weill Cornell Medicine
New York, NY

Dr. Carl F. Nathan is the chairman of the Microbiology and Immunology Department, and a professor of medicine at Weill Cornell Medicine. Among Dr. Nathan’s major accomplishments are discoveries concerning the roles of various factors—including IFN-g, TGF-B, and TNF-a—in the activity of immune cells, particularly macrophages, as well as the roles that reactive oxygen species play in anti-tumor and anti-microbial responses. In recognition of his contributions, he has been elected to the National Academy of Sciences, and his lab continues to focus on how macrophages carry out their protective effects, how this behavior is regulated, and what can cause it to fail. In addition to serving as an associate director of CRI’s Scientific Advisory Council, Dr. Nathan serves on the Postdoctoral Fellowship Review Committee.

We are interested in how macrophages kill, how killing is regulated and why killing is not always effective, [helping] to shape our basic understanding of innate immunity and host-pathogen interactions.
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