Michael L. Dustin, Ph.D.

University of Oxford
Oxford, United Kingdom

Dr. Michael L. Dustin is the director of Research at the Kennedy Institute of Rheumatology of the University of Oxford.

Dr. Dustin is known for his discovery of ICAM-1 (also known as CD54), which is involved in the integrin system necessary for immune cell migration. His other important contributions include identifying an antigen-dependent stop signal for T cells, and a description of the immunological synapse during T cell activation. Among other honors, he is a Fellow of the American Association for the Advancement of Science, and he continues to define how immune cells communicate and are regulated in different immune organs.

In addition to being a member of CRI’s Scientific Advisory Council, Dr. Dustin serves on the Postdoctoral Fellowship Review Committee.

The focus of our lab is to understand basic aspects of T cell activation, particularly the role of the immunological synapse- a stable interaction between immune cells that mediates signaling and effector function.
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