Dr. Michael L. Dustin is the director of Research at the Kennedy Institute of Rheumatology of the University of Oxford.
Dr. Dustin is known for his discovery of ICAM-1 (also known as CD54), which is involved in the integrin system necessary for immune cell migration. His other important contributions include identifying an antigen-dependent stop signal for T cells, and a description of the immunological synapse during T cell activation. Among other honors, he is a Fellow of the American Association for the Advancement of Science, and he continues to define how immune cells communicate and are regulated in different immune organs.
In addition to being a member of CRI’s Scientific Advisory Council, Dr. Dustin serves on the Postdoctoral Fellowship Review Committee.
The focus of our lab is to understand basic aspects of T cell activation, particularly the role of the immunological synapse- a stable interaction between immune cells that mediates signaling and effector function.
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