Jason G. Cyster, Ph.D.

University of California, San Francisco
San Francisco, CA

Jason G. Cyster, Ph.D., is a Professor in the Department of Microbiology and Immunology at the University of California, San Francisco.

Dr. Cyster is internationally recognized for defining how lymphoid microenvironments are organized to support adaptive immunity. He played a key role in the discovery of lymphoid tissue chemokines and established the concept that chemokines continuously guide cells to supportive niches. He led the way in defining how cells emigrate from lymphoid organs, a process essential for immune function. His group established the egress-promoting role of sphingosine-1-phosphate and identified the mechanism of action of key egress regulators. He has been a leader in applying two-photon microscopy to unraveling antigen-encounter and immune cell migration dynamics.

In recognition of this work he has been elected to the National Academy of Sciences and the American Academy of Arts and Sciences. His lab continues to study the immune cell migration and intercellular communication systems that maintain health and that become dysregulated in disease.

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