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Another CRI Scientist Receives AACR Award

March 25, 2014 | Alexandra Mulvey

Cancer immunology is coming into its own, as life-saving immunotherapies begin to transform cancer treatment. Several CRI scientists are receiving special honor this year for their important contributions to this revolution in treatment. These scientists have garnered three awards from the American Association for Cancer Research (AACR), to be given at the AACR Annual Meeting on April 5, 2014.

We recently reported here that CRI Scientific Advisory Council (SAC) members Robert D. Schreiber, Ph.D., and Jedd D. Wolchok, M.D., Ph.D., will receive the AACR-CRI Lloyd J. Old Award in Cancer Immunology and the AACR Richard and Hinda Rosenthal Memorial Award, respectively. We’re proud to share the news that AACR will also bestow the fifty-fourth annual AACR-G.H.A. Clowes Memorial Award on CRI SAC director, James P. Allison, Ph.D.

Dr. Allison is recognized for having laid the foundation for our ability to manipulate the T cell system for cancer therapeutics. In particular, he created antibodies to CTLA-4 and demonstrated the rejection of established tumors in several mouse model systems. He then developed an antibody to human CTLA-4, ipilimumab, which has been used in clinical trials in more than 4,000 patients with a variety of cancers including metastatic melanoma, prostate, lung, and ovarian cancers.

AACR and Eli Lilly established this award in 1961 to honor Dr. G.H.A. Clowes, who was a founding member of the AACR and a research director of Eli Lilly. The Clowes Award recognizes an individual with outstanding recent accomplishments in basic cancer research.

This award is one of a long list of honors Allison has received recently. Other recent awards include the 2014 Szent-Györgyi Prize by the National Foundation for Cancer Research, the 2014 Breakthrough Prize in Life Sciences, and the 2013 Innovations Award for Bioscience from the Economist magazine. In 2005, the Cancer Research Institute honored Allison with the William B. Coley Award for Distinguished Research in Basic and Tumor Immunology.  

Congratulations to Drs. Allison, Schreiber, and Wolchok!

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