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Therapeutic Cancer Vaccines

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img_table3_Therapeutic.pngTherapeutic cancer vaccines stimulate the immune system to attack cancer

How does it work?

  • Therapeutic cancer vaccines trigger the immune system to recognize and attack certain markers, or antigens, present on or in cancer cells
  • Unlike preventative vaccines, which help to prevent disease, therapeutic cancer vaccines treat disease that is already there
  • There are many different types of therapeutic cancer vaccines. Some are made of individual proteins; others are made of whole cells. One promising type is made of antigen-presenting cells called dendritic cells
  • Cancer vaccines often require additional substances called adjuvants for optimal effectiveness

For which cancers is it currently used or being studied?

  • The therapeutic cancer vaccine Provenge® is currently approved by the FDA to treat prostate cancer.
  • Therapeutic cancer vaccines are also being studied for treatment of the following cancers:
    • Non-Hodgkin’s lymphoma and mantle cell lymphoma (BioVaxID)
    • Breast (NeuVax)
    • Brain (DCVax, CDX-110) 
    • Pancreatic (GVAX Pancreas, HyperAcute™ Pancreas)
    • Colorectal (Imprime PGG®)
    • And many more

*Immunotherapy results may vary from patient to patient.