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Monday, September 15, 2008
Tuesday, September 16, 2008
Wednesday, September 17, 2008
| Day 1, September 15, 2008 |
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Opening Remarks and 75th Birthday Tribute to Lloyd J. Old, M.D.
Jill O'Donnell-Tormey
Transcript Play Audio in Browser Download Audio (.mp3)
Session I: Cancer Immunoediting and Cancer and Inflammation |
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| 9:00 a.m. |
Robert D. Schreiber |
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Washington University School of Medicine, St. Louis, MO |
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Cancer immunoediting: Molecular pathways to possible novel therapeutic interventions
Abstract Play Audio in Browser Download Audio (.mp3) |
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| 9:30 a.m. |
Adrian Hayday |
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Kings College School of Medicine at Guy's Hospital, London, UK |
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Molecules regulating the immunosurveillance of tissues
Abstract Play Audio in Browser Download Audio (.mp3) |
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| 10:00 a.m. |
Coffee Break |
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| 10:30 a.m. |
Mark J. Smyth |
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Peter MacCallum Cancer Centre, Victoria, Australia |
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Cancer immunoediting: Recent progress in elimination and equilibrium
Abstract Play Audio in Browser Download Audio (.mp3) |
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| 11:00 a.m. |
Glenn Dranoff |
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Dana-Farber Cancer Institute, Boston, MA |
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Balancing tumor immunity and inflammation
Abstract Play Audio in Browser Download Audio (.mp3) |
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| 11:30 a.m. |
Wolf H. Fridman |
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INSERM, University Paris Descartes and University Pierre et Marie Curie, Paris, France |
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Shaping an efficient adaptive immune microenvironment in human cancer
Abstract Play Audio in Browser Download Audio (.mp3) |
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| 12:00 p.m. |
Lunch |
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| Session II: Immunological Consequences of Current Cancer Therapy |
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| 2:00 p.m. |
Laurence Zitvogel |
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Institut Gustave Roussy, Villejuif, France |
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Is an anticancer immune response mandatory for therapeutic success?
Abstract Play Audio in Browser Download Audio (.mp3) |
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| 2:30 p.m. |
Hy Levitsky |
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John Hopkins University School of Medicine, Baltimore, MD |
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Lymphocyte homeostasis and tumor-specific immunity during immune reconstitution
Abstract Play Audio in Browser Download Audio (.mp3) |
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| 3:00 p.m. |
Coffee Break |
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| 3:30 p.m. |
Jeffrey V. Ravetch |
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The Rockefeller University, New York, NY |
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A general mechanism for anti-tumor therapy based on Fc receptor engagement
Abstract Play Audio in Browser Download Audio (.mp3) |
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| 4:00 p.m. |
Padmanee Sharma |
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The University of Texas M.D. Anderson Cancer Center, Houston, TX |
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Immunologic impact of anti-CTLA-4 antibody
Abstract Play Audio in Browser Download Audio (.mp3) |
| Day 2, September 16, 2008 |
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| Session III: Cross Presentation and Tumor Stroma |
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| 9:00 a.m. |
Michael J. Bevan |
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University of Washington School of Medicine, Seattle, WA |
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Antigen presentation and the T-cell response
Abstract Play Audio in Browser Download Audio (.mp3) |
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| 9:30 a.m. |
Pramod K. Srivastava |
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University of Connecticut Center for Immunotherapy of Cancer and Infectious Diseases, Farmington, CT |
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Molecular nature of the antigenic entity transferred from antigen donor cell to antigen presenting cells during cross presentation
Abstract Play Audio in Browser Download Audio (.mp3) |
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| 10:00 a.m. |
Günter J. Hämmerling |
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German Cancer Research Center, DKFZ Heidelberg, Heidelberg, Germany |
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Control of tumor immunity by the microenvironment: Overcoming the tumor endothelial barrier
Abstract Play Audio in Browser Download Audio (.mp3) |
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| 10:30 a.m. |
Coffee Break |
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| 11:00 a.m. |
George Coukos |
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University of Pennsylvania Medical Center, Philadelphia, PA |
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Open sesame: The endothelin (B) receptor mediates the tumor endothelial barrier to T-cell homing
Abstract Play Audio in Browser Download Audio (.mp3) |
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| 11:30 a.m. |
Ellen Puré |
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The Wistar Institute, Philadelphia, PA;
Ludwig Institute for Cancer Research, New York, NY |
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Targeting a stromal cell protease inhibits tumor growth
Abstract Play Audio in Browser Download Audio (.mp3) |
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| 12:00 p.m. |
Lunch |
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| Session IV: Modulators of Immune Escape Mechanisms |
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| 2:00 p.m. |
James P. Allison |
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Ludwig Center for Cancer Immunotherapy, Howard Hughes Medical Institute, Memorial Sloan-Kettering Cancer Center, New York, NY |
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Checkpoint blockade in tumor therapy: New insights and opportunities
Abstract Play Audio in Browser Download Audio (.mp3) |
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| 2:30 p.m. |
Vincenzo Bronte |
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Istituto Oncologico Veneto and Venetian Institute for Molecular Medicine, Padova, Italy |
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Myeloid-derived suppressor cells in cancer
Abstract Play Audio in Browser Download Audio (.mp3) |
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| 3:00 p.m. |
Coffee Break |
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| 3:30 p.m. |
Michail V. Sitkovsky |
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N.E. Inflammation and Tissue Protection Institute, Northeastern University, Boston, MA |
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The hypoxia-adenosinergic protection of tumors from anti-tumor T lymphocytes
Abstract Play Audio in Browser Download Audio (.mp3) |
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| 4:00 p.m. |
Arlene H. Sharpe |
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Harvard Medical School and Bringham and Women's Hospital, Boston, MA |
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PD-1, PD-L1 and their ligands: Regulating the balance between T-cell activation and tolerance
Abstract Play Audio in Browser Download Audio (.mp3) |
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| POSTER SESSION – 5:00 p.m., 8th Floor |
| Day 3, September 17, 2008 |
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| Session V: Adoptive Immunotherapy |
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| 9:00 a.m. |
Carl June |
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Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA |
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Updates in adoptive T cell therapy
Abstract Play Audio in Browser Download Audio (.mp3) |
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| 9:30 a.m. |
Michel Sadelain |
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Memorial Sloan-Kettering Cancer Center, New York, NY |
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Targeting tumors with genetically enhanced T lymphocytes
Abstract Play Audio in Browser Download Audio (.mp3) |
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| 10:00 a.m. |
Cassian Yee |
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Fred Hutchinson Cancer Research Center and University of Washington, Seattle, WA |
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Adoptive T cell therapy: Back to the future
Abstract Play Audio in Browser Download Audio (.mp3) |
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| 10:30 a.m. |
Coffee Break |
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| Session VI: Biomarkers and Novel Clinical Parameters in Immunotherapeutic Clinical Trials |
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| 11:00 a.m. |
David Berman |
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Bristol-Myers Squibb, Princeton, NJ |
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Potential biomarkers of immune activation in Ipilimumab-treated patients with advanced melanoma
Abstract Play Audio in Browser Download Audio (.mp3) |
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| 11:30 a.m. |
Sacha Gnjatic |
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Ludwig Institute for Cancer Research, Memorial Sloan-Kettering Cancer Center, New York, NY |
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Identification of immunogenic markers in pancreatic and ovarian cancer by seromics
Abstract Play Audio in Browser Download Audio (.mp3) |
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| 12:00 a.m. |
Kristen Hege |
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Cell Genesys, Inc., South San Francisco, CA |
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Potential biomarkers of response to GVAX immunotherapy for prostate cancer
Abstract Play Audio in Browser Download Audio (.mp3) |
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| 12:30 a.m. |
Lunch |
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| 2:00 p.m. |
Jedd Wolchok |
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Memorial Sloan-Kettering Cancer Center, New York, NY |
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New response criteria for immunotherapy to capture response patterns in advanced melanoma patients treated with Ipilimumab: Results from two phase II trials
Abstract Play Audio in Browser Download Audio (.mp3) |
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| 2:30 p.m. |
Cecile Gouttefangeas |
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University of Tuebingen, Tuebingen, Germany |
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Harmonized T-cell monitoring assays as biomarkers for immunotherapy trials: A data driven approach by the CIMT Immunoguiding Program (“CIP”)
Abstract Play Audio in Browser Download Audio (.mp3) |
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| 3:00 p.m. |
Frederic Lehmann |
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GlaxoSmithKline Biologicals, Rixensart, Belgium |
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Clinical response to the MAGE-A3 immunotherapeutic in metastatic melanoma patients is associated with a specific gene profile present prior to treatment
Abstract Play Audio (Pt. 1) in Browser Download Audio (Pt. 1) (.mp3)
Play Audio (Pt. 2) in Browser Download Audio (Pt. 2) (.mp3) |
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